Kempley S T, Gamsu H R
Children Nationwide Neonatal Centre, King's College Hospital, London.
Arch Dis Child. 1993 Jul;69(1 Spec No):74-6. doi: 10.1136/adc.69.1_spec_no.74.
Doppler ultrasound was used to measure blood flow velocity in the anterior cerebral artery of six premature infants with posthaemorrhagic hydrocephalus, before and after intermittent cerebrospinal fluid (CSF) drainage, on 23 occasions. There was a significant increase in mean blood flow velocity after the drainage procedures (+5.6 cm/s, 95% confidence interval +2.9 to +8.3 cm/s), which was accompanied by a decrease in velocity waveform pulsatility. CSF pressure also fell significantly. In patients with posthaemorrhagic hydrocephalus, intermittent CSF drainage was associated with acute changes in cerebral haemodynamics.
使用多普勒超声在23个不同时间点测量了6例出血后脑积水早产儿大脑前动脉的血流速度，测量时间为间歇性脑脊液（CSF）引流前后。引流术后平均血流速度显著增加（+5.6 cm/s，95%置信区间为+2.9至+8.3 cm/s），同时速度波形搏动性降低。脑脊液压力也显著下降。在出血后脑积水患者中，间歇性脑脊液引流与脑血流动力学的急性变化有关。
