Wheeler R A, Griffiths D M, Jackson A A
Wessex Regional Centre for Paediatric Surgery, London.
Arch Dis Child. 1993 Jul;69(1 Spec No):83-4. doi: 10.1136/adc.69.1_spec_no.83.
Urea kinetics were measured in a child with congenital absence of the colon on days 15, 19, and 23 of age. Urea salvage was 5% of urea production in the first study, increasing to 79% by the third. This provides evidence that the colonic microflora play a more active part in urea salvage than the mucosa and that the establishment of an active lower ileal microflora takes over some of the metabolic functions of the intact colon.
对一名先天性结肠缺失患儿在其15日龄、19日龄和23日龄时进行了尿素动力学测定。在首次研究中,尿素回收量为尿素生成量的5%,到第三次研究时增至79%。这证明结肠微生物群在尿素回收中比黏膜发挥着更积极的作用,并且活跃的回肠下段微生物群的建立接管了完整结肠的一些代谢功能。