Cosman A, Feliciano W C, Wolff M
Plast Reconstr Surg. 1977 Feb;59(2):255-9.
Four cases of skin ulceration in pentazocine addicts are presented. Appearing in broad areas of a peculiar wood induration and often massive in size, these ulcers can be clinically distinguished from comparable skin manifestations in other types of drug abuse. The histological finding of an obliterative vasculitis of the small vessels helps to explain the non-healing nature of these lesions. It also offers a rationale for the surgical therapy of wide excision, prior to skin grafting.
本文报告了4例喷他佐辛成瘾者的皮肤溃疡病例。这些溃疡出现在大面积的特殊木质硬结部位，且通常面积较大，在临床上可与其他类型药物滥用中类似的皮肤表现相区分。小血管闭塞性血管炎的组织学发现有助于解释这些病变不愈合的性质。这也为在植皮前进行广泛切除的手术治疗提供了理论依据。
