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[心绞痛患者在芬扑立定影响下左心室舒张功能及体力负荷耐受性的变化]

[Changes in left ventricular diastolic function and in tolerance to physical loading under the influence of finoptin in stenocardia patients].

作者信息

Lutaĭ M I, Lomakovskiĭ A N

出版信息

Eksp Klin Farmakol. 1993 Mar-Apr;56(2):30-2.

PMID:8348034
Abstract

A total of 45 patients aged 53.6 +/- 6.1 years who had Functional Class II-IV angina pectoris were examined. In patients with stable angina and normal left ventricular diastolic pressure, a moderate antianginal effect of finoptin was shown to be associated with decreased myocardial afterload. The normalizing effects of finoptin on baseline left ventricular diastolic dysfunction along with lower myocardial afterload resulted in an increase in coronary reserve and a more pronounced antianginal effect.

摘要

共检查了45例年龄为53.6±6.1岁、患有II-IV级功能性心绞痛的患者。在稳定型心绞痛且左心室舒张压正常的患者中,已表明芬诺普汀的中度抗心绞痛作用与心肌后负荷降低有关。芬诺普汀对基线左心室舒张功能障碍的正常化作用以及较低的心肌后负荷导致冠状动脉储备增加和更明显的抗心绞痛作用。

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