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[抗帕金森制剂对高压下氦氧环境中家兔自我刺激反应的影响]

[The effect of antiparkinson preparations on the self-stimulation reaction of rabbits in a helium-oxygen environment under increased pressure].

作者信息

Sledkov A Iu

出版信息

Eksp Klin Farmakol. 1993 Mar-Apr;56(2):64-6.

PMID:8348046
Abstract

The authors studied hypothalamic self-stimulation of 30 rabbits in hyperbaric heliox after intraperitoneal injections of L-DOPA, melanostatin, and cyclodol. The frequency of self-stimulation was decreased with 40 atm of heliox. After L-DOPA administration, a reduction of self-stimulation was twice less than that in heliox without pharmaceuticals.

摘要

作者对30只兔子在腹腔注射左旋多巴、黑素抑制素和安坦后，于高压氦氧环境下的下丘脑自我刺激情况进行了研究。在40个大气压的氦氧环境下，自我刺激频率降低。给予左旋多巴后，自我刺激的减少幅度比未用药的氦氧环境下小一半。

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