Andrade J L, Leal S M, Campos Filho O, Carvalho A C, Tebexreni A S, Lima V C
Pediatric Cardiology Division, Escola Paulista de Medicina, São Paulo, Brasil.
Cathet Cardiovasc Diagn. 1993 Jun;29(2):117-21. doi: 10.1002/ccd.1810290206.
Contrast echocardiography performed during cardiac catheterization has mostly been limited to a few published case reports. We studied 37 patients with congenital heart disease to assess the capability of the method to diagnose cardiac shunts and valve regurgitation. Injections of 5% dextrose in water through an angiographic catheter were made to evaluate septal integrity and valve competence compared with conventional contrast angiography. An overall sensitivity of 93% and specificity of 78% were found. In four cases of atrial septal defect and seven of mitral regurgitation, the sensitivity was 100%. It was slightly lower for eleven cases of ventricular septal defect (91%) and four of patent ductus arteriosus (75%). When assessing aortic, tricuspid and pulmonary valve competence, the method proved to be more sensitive than conventional angiography to detect mild regurgitation. Contrast echocardiography is a sensitive and safe technique that may be used in association with conventional angiography reducing the need for radiographic contrast and ionizing radiation time.
心导管检查期间进行的对比超声心动图大多局限于少数已发表的病例报告。我们研究了37例先天性心脏病患者，以评估该方法诊断心脏分流和瓣膜反流的能力。通过血管造影导管注入5%葡萄糖水溶液，与传统对比血管造影相比，以评估间隔完整性和瓣膜功能。结果发现总体敏感性为93%，特异性为78%。在4例房间隔缺损和7例二尖瓣反流病例中，敏感性为100%。对于11例室间隔缺损（91%）和4例动脉导管未闭（75%），敏感性略低。在评估主动脉瓣、三尖瓣和肺动脉瓣功能时，该方法被证明比传统血管造影更能敏感地检测轻度反流。对比超声心动图是一种敏感且安全的技术，可与传统血管造影联合使用，减少对放射造影剂的需求和电离辐射时间。
