Lau K W, Hung J S, Wu J J, Chern M S, Yeh K H, Fu M
Department of Cardiology, Chang Gung Medical College, Taiwan, Republic of China.
Cathet Cardiovasc Diagn. 1993 Jun;29(2):99-104. doi: 10.1002/ccd.1810290203.
This report describes a new balloon pulmonary valvuloplasty technique using the Inoue balloon catheter performed in 14 consecutive adult patients, aged 17-47 years (mean 27). The mean right ventricular systolic pressure and the pulmonary valvular peak-to-peak systolic gradient decreased from 102 +/- 41 to 52 +/- 19 mm Hg (p = 0.001) and 81 +/- 40 to 7 +/- 7 mm Hg (p = 0.0002), respectively. An infundibular peak-to-peak systolic gradient either developed (n = 13) or increased (n = 1). None of the patients were treated with beta-adrenergic blockers before or after the valvuloplasty. Eight patients underwent repeat hemodynamic study 12-30 months (mean 17) after treatment, and had no evidence of valvular restenosis. The mean right ventricular systolic pressure and the mean infundibular peak-to-peak systolic gradient decreased, compared to the values immediately after valvuloplasty (54 to 40 mm Hg, p = 0.03, and 28 to 10 mm Hg, p = 0.03, respectively). The study suggests that pulmonary valvuloplasty in adults using the Inoue balloon catheter technique is feasible, safe, and effective.
本报告描述了一种使用Inoue球囊导管对14例连续成年患者（年龄17 - 47岁，平均27岁）进行的新型球囊肺动脉瓣成形术技术。平均右心室收缩压和肺动脉瓣峰 - 峰收缩期压差分别从102±41降至52±19 mmHg（p = 0.001）和81±40降至7±7 mmHg（p = 0.0002）。13例患者出现漏斗部峰 - 峰收缩期压差，1例患者压差增加。在瓣膜成形术前后，所有患者均未接受β - 肾上腺素能阻滞剂治疗。8例患者在治疗后12 - 30个月（平均17个月）接受了重复血流动力学研究，未发现瓣膜再狭窄的证据。与瓣膜成形术后即刻的值相比，平均右心室收缩压和平均漏斗部峰 - 峰收缩期压差降低（分别为54至40 mmHg，p = 0.03，以及28至10 mmHg，p = 0.03）。该研究表明，使用Inoue球囊导管技术对成人进行肺动脉瓣成形术是可行、安全且有效的。
