Flanders M, Chin D, Boghen D
Department of Ophthalmology, Montreal Children's Hospital, McGill University, Que., Canada.
Eur Neurol. 1993;33(4):316-9. doi: 10.1159/000116961.
This paper retrospectively analyses the clinical data of 65 consecutive cases of hemifacial spasm. A benign etiology was clinically evident in the majority of cases. Neuroradiologic investigation ruled out serious intracranial pathology in atypical cases. Trials of oral medication in 26 patients were consistently unsuccessful. Fifty-one patients had repeated lid and facial muscle injections of botulinum toxin during a period of 8 years. The mean duration of effective relief from spasm following an initial treatment was 18.9 weeks. This effect did not diminish with repeated injections.
本文回顾性分析了65例连续性面肌痉挛患者的临床资料。大多数病例临床上病因良性明显。神经放射学检查排除了非典型病例中的严重颅内病变。26例患者口服药物试验均未成功。51例患者在8年期间反复进行肉毒杆菌毒素眼睑及面部肌肉注射。首次治疗后痉挛有效缓解的平均持续时间为18.9周。这种效果不会因反复注射而减弱。
