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A radiographic and histologic study of fracture healing in osteopetrotic rats.

作者信息

Schmidt C J, Marks S C, Jordan C A, Hawes L E

出版信息

Radiology. 1977 Feb;122(2):517-9. doi: 10.1148/122.2.517.

DOI:10.1148/122.2.517
PMID:834906
Abstract

Repair of tibial fractures in osteopetrotic rats was delayed in comparison to that of normal littermates, due to reduced remodeling. Reduced bone resorption, known to be the cause of the disease in this mutation, is expressed in both skeletal development and fracture repair. The possible implications for human juvenile osteopetrosis are discussed.

摘要

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Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.局部低剂量洛伐他汀递送可改善成骨细胞中 NF1 功能丧失引起的骨愈合缺陷。
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Valgus tibial osteotomy in a patient with benign dominant osteopetrosis (Albers-Schoenberg disease). A case report.
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Int Orthop. 1994 Oct;18(5):304-7. doi: 10.1007/BF00180231.