Kudoh A, Kimura F, Murakawa T, Ishihara H, Matsuki A
Department of Anesthesiology, Hakodate Watanabe Hospital.
Masui. 1993 Jul;42(7):1056-64.
We experienced perioperative management of thirty two surgical patients complicated with either schizophrenia or depression on long-term administration of psychotropic drugs during a period of three years from 1989 through 1991. They underwent various operative procedures under either general anesthesia or epidural anesthesia. Mental confusion was most frequently encountered in immediate postoperative period. The longer the patients had been treated with psychotropic drugs, the more postoperative complications were observed. We lost four patients within two weeks postoperatively. They all underwent laparotomy and had been treated with psychotropic drugs for a prolonged period. No significant association between the types of anesthesia and postoperative complications was observed. Surgical patients on long-term administration of psychotropic drugs should be managed carefully particularly during postoperative period.
1989年至1991年的三年间,我们对32例长期服用精神药物并发精神分裂症或抑郁症的外科手术患者进行了围手术期管理。他们在全身麻醉或硬膜外麻醉下接受了各种手术。术后即刻最常出现精神错乱。患者服用精神药物的时间越长,观察到的术后并发症就越多。我们在术后两周内失去了4例患者。他们均接受了剖腹手术,且长期服用精神药物。未观察到麻醉类型与术后并发症之间存在显著关联。长期服用精神药物的外科手术患者应特别在术后期间进行仔细管理。