Kanno T
Department of Laboratory Medicine, Hamamatsu University, School of Medicine.
Rinsho Byori. 1993 May;41(5):588-91.
Characteristics of small scale or regional quality control (QC) programs are quick responses to resolving QC problems and cooperation. In this paper, we illustrated and discussed the positive results of the regional QC program in Shizuoka prefecture as a model for small scale QC assurance programs. Kitamura's allowable limitations for analytical error in internal QC were estimated from the physiological and technical variation of individual assays and compared with the coefficient of variation (CV) of each analyte in clinical laboratories. CV of analytes in 80% of the laboratories cleared Kitamura's allowable limitation with the exception of alkaline phosphatase and calcium. Many laboratories are now making extensive efforts toward clearing the allowable limitation in these two items. Many working groups (WG), such as enzymes, immunochemistry, and ion selective electrode WG, are very active in resolving problems found by QC programs. The results obtained in these working groups were effectively communicated to the clinical laboratories and bedside physicians. These responses in small QC program are surely complementary to large scale QC programs such as the QC program of the Japan Medical Association.
小规模或区域质量控制（QC）项目的特点是对解决QC问题反应迅速且注重合作。在本文中，我们阐述并讨论了静冈县区域QC项目的积极成果，将其作为小规模QC保证项目的典范。北村根据各个检测项目的生理和技术变异估算了内部QC分析误差的允许限度，并与临床实验室中各分析物的变异系数（CV）进行比较。除碱性磷酸酶和钙外，80%实验室中分析物的CV清除了北村的允许限度。目前许多实验室正在为清除这两个项目的允许限度做出广泛努力。许多工作组（WG），如酶学、免疫化学和离子选择性电极工作组，在解决QC项目发现的问题方面非常活跃。这些工作组获得的结果有效地传达给了临床实验室和床边医生。这些小规模QC项目的反应无疑是对诸如日本医学协会QC项目等大规模QC项目的补充。
