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曼海姆腹膜炎指数在印度一家乡村医院对穿孔性腹膜炎患者预后预测中的作用

The Role of the Mannheim Peritonitis Index for Predicting Outcomes in Patients With Perforation Peritonitis in a Rural Hospital in India.

作者信息

Ramteke Harshal, Deshpande Swati G, Bhoyar Rohini

机构信息

General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Obstetrics and Gynaecology, NKP Salve Institute of Medical Sciences, Nagpur, IND.

出版信息

Cureus. 2023 Mar 24;15(3):e36620. doi: 10.7759/cureus.36620. eCollection 2023 Mar.

Abstract

Introduction Acute secondary peritonitis due to hollow viscus perforation is a life-threatening surgical condition with significant morbidity and mortality, depending on the severity with outcomes that differ in the Western and developing world. Various scoring systems have been developed to assess the severity and its relation to morbidity and mortality. We conducted this study to evaluate the role of the Mannheim peritonitis index (MPI) in predicting outcomes in perforation peritonitis patients in a rural hospital in India. Materials and methods A prospective study of 50 patients with hollow viscus perforation with secondary peritonitis presented to the emergency department, Acharya Vinoba Bhave Rural Hospital, Sawangi (Meghe), Wardha, from 2016 to 2020. Each operated patient was scored according to the MPI to predict mortality. Results The majority of the patients were discharged uneventfully and about 16% (8/50) of the patients expired. The patients with an MPI score of more than 29 had maximum mortality of 62.5%. Mortality was seen in 37.5% of the patients with MPI scores between 21 and 29, whereas no mortality was recorded in patients with an MPI score of 21. Higher mortality was associated with age greater than 50 years (p=0.007), the presence of malignancy (p=0.013), colonic perforation (p=0.014), and fecal contamination (p=0.004). There was no significant correlation with gender (p=0.81), the presence of organ failure (p=1.6), delayed presentation, i.e., preoperative duration >24 hours (p=0.17), and the presence of diffuse peritonitis (p=0.25). Conclusion MPI is a specific, easily reproducible, and less cumbersome scoring method for predicting mortality in patients with hollow viscus perforation (secondary) peritonitis with minimal laboratory investigations. Higher scores correlate with a poorer prognosis and need intensive management, making use of MPI in clinical practice relevant and beneficial, especially in resource-poor settings.

摘要

引言 因中空脏器穿孔导致的急性继发性腹膜炎是一种危及生命的外科疾病,其发病率和死亡率都很高,其严重程度在西方和发展中世界有所不同,预后也存在差异。已经开发了各种评分系统来评估疾病的严重程度及其与发病率和死亡率的关系。我们开展这项研究以评估曼海姆腹膜炎指数(MPI)在印度一家农村医院预测穿孔性腹膜炎患者预后中的作用。

材料与方法 对2016年至2020年期间在沃德哈县萨万吉(梅格)的阿查里亚·维诺巴·巴韦农村医院急诊科就诊的50例因中空脏器穿孔导致继发性腹膜炎的患者进行了一项前瞻性研究。根据MPI对每位接受手术的患者进行评分以预测死亡率。

结果 大多数患者顺利出院,约16%(8/50)的患者死亡。MPI评分超过29分的患者死亡率最高,为62.5%。MPI评分在21至29分之间的患者死亡率为37.5%,而MPI评分为21分的患者未记录到死亡病例。较高的死亡率与年龄大于50岁(p=0.007)、存在恶性肿瘤(p=0.013)、结肠穿孔(p=0.014)和粪便污染(p=0.004)相关。与性别(p=0.81)、存在器官衰竭(p=1.6)、就诊延迟(即术前时长>24小时,p=0.17)以及弥漫性腹膜炎(p=0.25)无显著相关性。

结论 MPI是一种特异性强、易于重复且操作简便的评分方法,用于预测中空脏器穿孔(继发性)腹膜炎患者的死亡率,所需实验室检查最少。较高的评分与较差的预后相关,需要强化管理,在临床实践中使用MPI具有相关性且有益,尤其是在资源匮乏的环境中。

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