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维生素E烟酸酯与维生素E和烟酸组合对过氧化氢诱导的血小板聚集影响的比较研究

A comparative study of the effect of vitamin E-nicotinate and the combination of vitamin E and nicotinic acid on the hydrogen peroxide-induced platelet aggregation.

作者信息

Higashi O, Kikuchi Y

出版信息

Tohoku J Exp Med. 1977 Jan;121(1):81-4. doi: 10.1620/tjem.121.81.

DOI:10.1620/tjem.121.81
PMID:835140
Abstract

The inhibitory effect of vitamin E-nicotinate upon the hydrogen peroxide (H2O2)-induced platelet aggregation was found to be greater than that of either vitamin E alone or the combination of vitamin E and nicotinic acid. Nicotinic acid showed no inhibitory effect. It was suggested that the effect of vitamin E-nicotinate was not due to the additive effect of vitamin E and nicotinic acid produced by hydrolysis, but to the unique and distinctive property of vitamin E-nicotinate itself.

摘要

发现维生素E烟酸酯对过氧化氢(H2O2)诱导的血小板聚集的抑制作用大于单独的维生素E或维生素E与烟酸组合的抑制作用。烟酸未显示出抑制作用。有人提出,维生素E烟酸酯的作用并非由于水解产生的维生素E和烟酸的加和作用,而是由于维生素E烟酸酯本身独特的性质。

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1
A comparative study of the effect of vitamin E-nicotinate and the combination of vitamin E and nicotinic acid on the hydrogen peroxide-induced platelet aggregation.维生素E烟酸酯与维生素E和烟酸组合对过氧化氢诱导的血小板聚集影响的比较研究
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