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[心力衰竭中的血流动力学:收缩功能障碍和舒张功能障碍]

[Hemodynamics in heart failure: systolic and diastolic dysfunction].

作者信息

Hess O M

机构信息

Departement für Innere Medizin, Kardiologie, Universitätspital Zürich.

出版信息

Ther Umsch. 1993 Jun;50(6):414-8.

PMID:8351672
Abstract

Cardiac insufficiency is hemodynamically characterised by reduced cardiac output and increased diastolic filling pressure at rest and/or during physical activity. The increase in diastolic filling pressure compensates cardiac output and is either a result of increased initial tension of muscle fibers (Frank-Starling's Law) or a sign of decreased myocardial compliance. Increased initial tension of muscle fibers is a sign of systolic insufficiency, whereas reduced ventricular compliance indicates a disorder of diastolic ventricular function. In systolic insufficiency (= systolic dysfunction) a decrease in the ventricular ejection fraction is important, as is an increase in filling pressure. In diastolic congestive heart failure (= diastolic dysfunction) a reduced ventricular compliance with normal stroke function is typical.

摘要

心脏功能不全在血流动力学上的特征是静息和/或体力活动时心输出量减少以及舒张期充盈压升高。舒张期充盈压的升高可代偿心输出量,这要么是肌纤维初始张力增加(弗兰克 - 斯塔林定律)的结果,要么是心肌顺应性降低的表现。肌纤维初始张力增加是收缩功能不全的表现,而心室顺应性降低则表明舒张期心室功能障碍。在收缩功能不全(=收缩功能障碍)中,心室射血分数降低很重要,充盈压升高也很重要。在舒张性充血性心力衰竭(=舒张功能障碍)中,典型表现是心室顺应性降低而搏出功能正常。

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