Iwata F, Hanawa Y, Takashima H
Department of Pediatrics, Tobu Regional Hospital, Tokyo, Japan.
Acta Paediatr Jpn. 1993 Jun;35(3):252-7. doi: 10.1111/j.1442-200x.1993.tb03047.x.
A 13 year old girl with carpopedal spasm is presented. Investigation values showed hypomagnesemia and hypokalemia. Her younger brother and sister demonstrated the same biochemical abnormalities without any symptoms. Their urinary excretion of magnesium and potassium were inappropriately high compared with their serum levels. Treatment with oral magnesium sulfate failed to correct the abnormalities, but serum levels of magnesium and potassium were just below the lower limits. This familial disease may represent congenital renal wasting of magnesium and potassium.
一名13岁患有手足痉挛的女孩前来就诊。检查结果显示低镁血症和低钾血症。她的弟弟和妹妹也有同样的生化异常，但没有任何症状。与他们的血清水平相比，他们尿中镁和钾的排泄量异常高。口服硫酸镁治疗未能纠正这些异常，但镁和钾的血清水平仅略低于下限。这种家族性疾病可能代表先天性肾性镁和钾流失。
