卡尔曼综合征：嗅觉系统的磁共振成像评估
Kallmann syndrome: MR evaluation of olfactory system.
作者信息
Yousem D M, Turner W J, Li C, Snyder P J, Doty R L
机构信息
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
出版信息
AJNR Am J Neuroradiol. 1993 Jul-Aug;14(4):839-43.
PURPOSE
To describe the MR appearance of the olfactory bulbs and tracts and temporal lobes in patients with Kallmann syndrome, a disorder characterized by hypogonadotropic hypogonadism and anosmia.
METHODS
High-resolution MR scans with a surface coil placed over the nasion were performed in two patients with Kallmann syndrome. Coronal 3-mm thick contiguous sections were obtained through the olfactory bulbs and tracts. MR scans included volumetric analysis of the bulbs, tracts, temporal lobes, and hippocampi.
RESULTS
No olfactory bulbs or tracts could be identified in patients with Kallmann syndrome. In comparison, the olfactory bulbs and tracts were identifiable in seven healthy volunteers. The temporal lobe and hippocampal volumes were comparable between control subjects and Kallmann patients.
CONCLUSIONS
High-resolution surface-coil MR can identify the absence of olfactory bulbs and tracts in patients with Kallmann syndrome. Normal olfactory bulbs and tracts are easily discerned with surface-coil imaging.
目的
描述卡尔曼综合征患者嗅球、嗅束及颞叶的磁共振成像（MR）表现。卡尔曼综合征是一种以低促性腺激素性性腺功能减退和嗅觉缺失为特征的疾病。
方法
对两名卡尔曼综合征患者进行了高分辨率MR扫描，将表面线圈置于鼻根上方。通过嗅球和嗅束获取3毫米厚的连续冠状位切片。MR扫描包括对嗅球、嗅束、颞叶和海马的体积分析。
结果
卡尔曼综合征患者未发现嗅球或嗅束。相比之下，在七名健康志愿者中可识别出嗅球和嗅束。对照组和卡尔曼综合征患者的颞叶和海马体积相当。
结论
高分辨率表面线圈MR可识别卡尔曼综合征患者嗅球和嗅束的缺失。表面线圈成像可轻松辨别正常的嗅球和嗅束。
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