Weber W
Clinical Cancer Research Unit, Basel, Switzerland.
Anticancer Res. 1993 Jul-Aug;13(4):1197-201.
Family history can be used to identify persons at high cancer risk and to target appropriate preventive and therapeutic measures. First-degree female relatives of women with breast cancer (n = 600) are at increased risk for breast cancer (RR: 1.7.95% CI: 1.4-1.9). First-degree relatives of colorectal cancer patients (n = 184) are at increased risk for colorectal cancer (RR: 1.8.95% CI: 1.4-2.3). Families with hereditary cancer syndromes are identified. The family history approach can be used in every part of the world, and it should become a part of future cancer control activities.
家族史可用于识别癌症高危人群,并针对性地采取适当的预防和治疗措施。乳腺癌女性患者的一级女性亲属(n = 600)患乳腺癌的风险增加(相对危险度:1.7,95%置信区间:1.4 - 1.9)。结直肠癌患者的一级亲属(n = 184)患结直肠癌的风险增加(相对危险度:1.8,95%置信区间:1.4 - 2.3)。可识别出患有遗传性癌症综合征的家族。家族史方法可在世界各个地区使用,并且应成为未来癌症控制活动的一部分。