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[猫慢性电刺激后的耳蜗病理学]

[Cochlear pathology following chronic electrical stimulation in cats].

作者信息

Ni D F

机构信息

PUMC Hospital, Beijing.

出版信息

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(1):11-3, 58.

PMID:8352990
Abstract

This study is to follow the faults during safe research of chronic electrical stimulation of auditory nerve. They were surgical trauma; electrode excursion from scala tympani in different periods after insertion, direct current trauma to the cochleas during chronic electrical stimulation due to the stimulator fault. Extensive histopathological changes were observed, including widespread hair cell and spiral ganglion loss and new bone growth. These results have important implications both in the use and design of cochlear prostheses.

摘要

本研究旨在追踪听神经慢性电刺激安全性研究过程中的故障。这些故障包括手术创伤;电极在插入后不同时期从鼓阶移位、慢性电刺激期间由于刺激器故障对耳蜗造成的直流电损伤。观察到广泛的组织病理学变化,包括广泛的毛细胞和螺旋神经节丢失以及新骨生长。这些结果对人工耳蜗的使用和设计都具有重要意义。

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