Stephenson T, Stammers J, Hull D
Department of Child Health, University Hospital, Nottingham, UK.
Biol Neonate. 1993;63(5):273-80. doi: 10.1159/000243941.
Free fatty acids (FFA) are the main class of naturally occurring lipids transferred across the placenta, irrespective of species. In order to study the importance of fetal plasma albumin concentration and pH on placental transfer of FFA, in situ perfusion of the rabbit placenta in late gestation was used as an experimental model. Increasing albumin concentration on the fetal side of the placenta from 1 to 6% significantly increased transfer of FFA across the placenta. However, alteration of the umbilical perfusate pH in the range 7.0-7.5 had no significant effect.
游离脂肪酸（FFA）是跨胎盘转运的主要一类天然存在的脂质，与物种无关。为了研究胎儿血浆白蛋白浓度和pH值对FFA胎盘转运的重要性，将妊娠晚期兔胎盘原位灌注作为实验模型。胎盘胎儿侧白蛋白浓度从1%增加到6%显著增加了FFA跨胎盘的转运。然而，脐灌注液pH值在7.0 - 7.5范围内的改变没有显著影响。
