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[CA 19-9肿瘤标志物在胰腺癌诊断中的应用]

[Use of the CA 19-9 tumor marker in the diagnosis of pancreatic carcinoma].

作者信息

Kausitz J, Lesný P, Belan V

机构信息

Subkatedra nukleárnej medicíny ILF v Bratislave, Slovakia.

出版信息

Bratisl Lek Listy. 1993 Apr;94(4):201-3.

PMID:8353764
Abstract

The contribution of the tumor marker CA 19-9 to differential diagnosis between malignant and nonmalignant diseases of the pancreas was assessed in a group of 120 patients. On using border values of CA 19-9 80 U/ml, its sensitivity was found to be 84.4% and its specificity 84.8% for carcinomas of the pancreas. Correlation of CA 19-9 values with results of computer tomography and endogenous retrograde cholangiopancreatography in the patients studied yielded an over 80% accordance. In the light of the obtained results, the authors consider determination of CA 19-9 levels to be a suitable method supplementing the imaging examination methods in suspect carcinoma of the pancreas.

摘要

在一组120例患者中评估了肿瘤标志物CA 19-9对胰腺良恶性疾病鉴别诊断的贡献。以CA 19-9 80 U/ml的临界值使用时,发现其对胰腺癌的敏感性为84.4%,特异性为84.8%。所研究患者的CA 19-9值与计算机断层扫描及内镜逆行胰胆管造影结果的相关性超过80%相符。根据所得结果,作者认为测定CA 19-9水平是补充疑似胰腺癌影像检查方法的合适方法。

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