Toivanen A, Yli-Kerttula T, Luukkainen R, Merilahti-Palo R, Granfors K, Seppälä J
Department of Medicine, Turku University Central Hospital, Finland.
Clin Exp Rheumatol. 1993 May-Jun;11(3):301-7.
In a double-blind study comprising 36 patients the effect of a three-month course of ciprofloxacin on chronic reactive arthritis was evaluated. At the end of the follow-up period 6 months after stopping the therapy, arthralgia, pain at movement and morning stiffness had decreased significantly compared to the values before the treatment in the ciprofloxacin group, whereas the Ritchie index and ESR showed a significant decrease in the control group. We conclude that further studies are necessary before the value of prolonged ciprofloxacin treatment of chronic reactive arthritis can be established.
在一项纳入36例患者的双盲研究中，评估了为期三个月的环丙沙星疗程对慢性反应性关节炎的疗效。在停止治疗6个月后的随访期结束时，与环丙沙星组治疗前的值相比，关节痛、活动时疼痛和晨僵明显减轻，而对照组的里奇指数和红细胞沉降率显著下降。我们得出结论，在确定环丙沙星长期治疗慢性反应性关节炎的价值之前，有必要进行进一步的研究。
