Wei X Y
Institute of Labor Health of Baiyin, Nonferrous Metals Company, Gansu.
Zhonghua Yu Fang Yi Xue Za Zhi. 1993 Mar;27(2):88-90.
The results of determination of the bone density of 194 workers exposed to fluorine by SPA-III type osteodensimeter were compared with people unexposed to fluorine, and with the results of diagnosing the luorosis by X-ray. (1) The abnormal bone cortex thickness and density rate in the people exposed to fluorine was significantly higher than the ordinary people (P < 0.05). (2) In the people exposed to fluorine, the correspondency rate of determining fluorosis of bone by X-ray and by osteodensimeter were 84.6%, and results of the two methods had no significant difference (P > 0.05). (3) In another group of 155 cases, whose values of hair fluorine and urinary fluorine were higher than the ordinary people (66.5%), the abnormal density of bone of 103 cases had been determined by osteodensimeter, but not by X-ray. This showed that the diagnosis of early changes of osteofluorosis by osteodensimeter was more sensitive than by X-ray. (4) There was close association between the unusual rate of osteodensity and the superstandard rate of hair fluorine and urinary fluorine. The above findings indicated the determination of bone density can be used as a diagnostic index for occupational fluorosis.
采用SPA-III型骨密度仪对194名接触氟的工人进行骨密度测定，并与未接触氟的人群进行比较，同时与X线诊断氟骨症的结果进行比较。（1）接触氟人群的骨皮质厚度和密度异常率明显高于正常人（P<0.05）。（2）在接触氟人群中，X线与骨密度仪诊断骨氟中毒的符合率为84.6%，两种方法结果差异无统计学意义（P>0.05）。（3）另一组155例，发氟和尿氟值高于正常人（66.5%），骨密度仪测定103例骨密度异常，X线未显示异常。这表明骨密度仪诊断早期氟骨症变化比X线更敏感。（4）骨密度异常率与发氟、尿氟超标率之间存在密切关联。上述结果表明，骨密度测定可作为职业性氟中毒的诊断指标。
