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免疫组化技术在髓内施万细胞瘤中的诊断效用

Diagnostic utility of immunohistochemical techniques in intramedullary Schwann-cell tumours.

作者信息

Radhakrishnan V V, Saraswathy A, Radhakrishnan N S, Rout D

机构信息

Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum.

出版信息

Indian J Pathol Microbiol. 1993 Jan;36(1):87-91.

PMID:8354567
Abstract

Histopathologic features in two intramedullary schwann-cell tumours, closely resembled with those of fibrillary astrocytoma and could not be differentiated from each other by the conventional histochemical stains. However application of tumour markers-Glial fibrillary acidic protein (GFAP) and S-100 protein were found to be useful in differentiating these two tumours and thus helped in making an accurate histopathological diagnosis in these two patients.

摘要

两个髓内施万细胞瘤的组织病理学特征与纤维型星形细胞瘤极为相似,通过传统组织化学染色无法相互区分。然而,发现应用肿瘤标志物——胶质纤维酸性蛋白(GFAP)和S-100蛋白有助于鉴别这两种肿瘤,从而有助于对这两名患者做出准确的组织病理学诊断。

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