浣熊（北美浣熊）对源自臭鼬的狂犬病病毒易感性及条纹臭鼬（北美臭鼬）相对易感性的进一步研究

Further studies on the susceptibility of raccoons (Procyon lotor) to a rabies virus of skunk origin and comparative susceptibility of striped skunks (Mephitis mephitis).

作者信息

Hill R E, Smith K E, Beran G W, Beard P D

机构信息

Biotechnology, Biologics, and Environmental Protection, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Ames, Iowa 50010.

出版信息

J Wildl Dis. 1993 Jul;29(3):475-7. doi: 10.7589/0090-3558-29.3.475.

DOI:10.7589/0090-3558-29.3.475

PMID:8355351

Abstract

Two raccoons (Procyon lotor) were inoculated in the masseter muscles with 10(5.9) mouse intracerebral lethal dose50 (MICD50) of a rabies virus isolated from a naturally infected Iowa (USA) striped skunk (Mephitis mephitis). Five striped skunks were inoculated with either 10(0.7) or 10(2.1) MICLD50 of the same isolate. All five skunks died within 35 days following inoculation. Both raccoons survived 273 days without adverse effects, and virus was not isolated from saliva samples taken at between 25 and 273 days following inoculation.

摘要

用从一只自然感染的美国爱荷华州带条纹臭鼬（臭鼬属）分离出的狂犬病病毒的10(5.9)小鼠脑内致死剂量50（MICD50），对两只浣熊（北美浣熊）的咬肌进行接种。用同一毒株的10(0.7)或10(2.1) MICLD50对五只带条纹臭鼬进行接种。所有五只臭鼬在接种后35天内死亡。两只浣熊存活了273天且无不良反应，在接种后25至273天采集的唾液样本中未分离到病毒。