Serra Batlles J, Comella A, Casas J C, Plaza V, Brugués J
Sección de Neumología, Hospital General de Vic, Barcelona.
Med Clin (Barc). 1993 Jun 19;101(4):125-7.
Aerosol inhalers constitute the most commonly used form of administration of medication by most of the patients with respiratory disease although incorrect usage is a demonstrated fact in many studies. A previous study demonstrated that, despite correct instruction by health care staff and the patients, 30% of the same use these inhalers incorrectly. In the present study, the efficacy of inhalation chambers (750 ml) and spacers (50 ml) versus the conventional inhaler was evaluated by quantification of bronchodilator response.
Fifty-six stable patients with chronic obstruction to air flow in habitual treatment with aerosol inhalers (AI) were studied. For this study 27 patients used the chamber and 29 the spacer. The patients using the maneuvers correctly (n = 42) and those that did not (n = 14) were studied together and separately.
Patients using the inhaler incorrectly were found to benefit significantly from either of the procedures. Upon comparison of the chambers (750 ml) with the spacers (50 ml) a significant improvement was observed with the former.
The response to bronchodilator treatment in patients not using aerosol inhalers correctly improves significantly upon use of either inhalation chambers or spacers with the former demonstrating the best results.
气雾剂吸入器是大多数呼吸系统疾病患者最常用的给药方式，尽管许多研究表明存在使用不当的情况。先前的一项研究表明，尽管医护人员和患者都接受了正确的指导，但仍有30%的患者使用这些吸入器的方法不正确。在本研究中，通过对支气管扩张剂反应进行量化，评估了吸入室（750毫升）和储雾罐（50毫升）相对于传统吸入器的疗效。
对56名稳定的慢性气流受限患者进行了研究，这些患者习惯性使用气雾剂吸入器（AI）。在本研究中，27名患者使用吸入室，29名患者使用储雾罐。对正确使用操作方法的患者（n = 42）和未正确使用的患者（n = 14）进行了综合研究和分别研究。
发现使用吸入器方法不正确的患者从这两种操作方法中均显著获益。将750毫升的吸入室与50毫升的储雾罐进行比较时，发现前者有显著改善。
不正确使用气雾剂吸入器的患者在使用吸入室或储雾罐后，支气管扩张剂治疗反应显著改善，其中吸入室的效果最佳。
