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The usefulness of stool screening for diagnosing cholelithiasis in acute pancreatitis. A description of the technique.

作者信息

Acosta M J, Rossi R, Ledesma C L

出版信息

Am J Dig Dis. 1977 Feb;22(2):168-72. doi: 10.1007/BF01072962.

DOI:10.1007/BF01072962
PMID:835559
Abstract

Screening stools for gallstones in patients with acute pancreatitis has been found to be a valuable diagnostic procedure in clinical practice. It is particularly helpful to know that a patient with pancreatitis has gallstones and, therefore, the disease is probably caused by the passage of these stones. A detailed description of the technique employed for stool screening is presented. The procedure was applied in 51 patients recovering from an attack of gallstone pancreatitis,in 51 control patients with known gallstones disease but without acute pancreatitis, and also in 10 patients with acute alcoholic pancreatitis Gallstones were found in the feces in 47 of the 51 patients with gallstone pancreatitis (92.1%), in only 6 of the 51 control cases (11.8%) (chi square = 62.84; P less than 0.0001), and in none of the 10 patients with alcoholic pancreatitis. In the group with gallstone pancreatitis, the finding occurred within 10 days after the attack. Oral cholecystography was also accomplished an average of 12.7 days after the attack in 38 of the 61 pancreatitis patients (28 with biliary and 10 with alcoholic pancreatitis). In 27 of the 28 patients with gallstone pancreatitis (96.4%) and in 4 of the 10 patients with alcoholic pancreatitis, radiologic evidence of cholelithiasis was found. There were 19 patients with gallstone pancreatitis who did not have a cholecystogram accomplished because of jaundice, recurrent pancreatitis, previous cholecystectomy, and pregnancy. These results suggest that screening stools is as accurate and reliable as cholecystography for the diagnosis of gallstones in individuals with pancreatitis. In addition, this method has three definite advantages over cholecystography: There are no contraindications; it requires no special equipment or personnel; and it can be used much earlier than cholecystography in patients recovering from an attack of acute pancreatitis. Screening stools for gallstones should be considered an elective diagnostic procedure for current clinical application.

摘要

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Are liver function tests, pancreatitis and cholecystitis predictors of common bile duct stones? Results of a prospective, population-based, cohort study of 1171 patients undergoing cholecystectomy.

本文引用的文献

1
Gallstone migration as a cause of acute pancreatitis.胆结石迁移作为急性胰腺炎的一个病因
N Engl J Med. 1974 Feb 28;290(9):484-7. doi: 10.1056/NEJM197402282900904.
肝功能检查、胰腺炎和胆囊炎是否是胆总管结石的预测因素?对 1171 例行胆囊切除术的患者进行前瞻性、基于人群的队列研究的结果。
HPB (Oxford). 2011 Aug;13(8):519-27. doi: 10.1111/j.1477-2574.2011.00317.x. Epub 2011 May 11.
4
Etiology and diagnosis of acute biliary pancreatitis.急性胆源性胰腺炎的病因和诊断。
Nat Rev Gastroenterol Hepatol. 2010 Sep;7(9):495-502. doi: 10.1038/nrgastro.2010.114. Epub 2010 Aug 10.
5
Acute biliary pancreatitis: diagnosis and treatment.急性胆源性胰腺炎:诊断与治疗
Saudi J Gastroenterol. 2009 Jul-Sep;15(3):147-55. doi: 10.4103/1319-3767.54740.
6
Treatment of common bile duct stones discovered during cholecystectomy.胆囊切除术中发现的胆总管结石的治疗。
J Gastrointest Surg. 2008 Apr;12(4):624-8. doi: 10.1007/s11605-007-0452-0. Epub 2008 Jan 5.
7
Intraoperative cholangiography facilitates simple transcystic clearance of ductal stones in units without expertise for laparoscopic bile duct surgery.术中胆管造影有助于在缺乏腹腔镜胆管手术专业技术的单位对胆管结石进行简单的经胆囊清除。
Surg Endosc. 2007 Jun;21(6):955-9. doi: 10.1007/s00464-006-9127-2. Epub 2007 Feb 7.
8
Pancreatic and bile duct obstruction exacerbates rat caerulein-induced pancreatitis: a new experimental model of acute hemorrhagic pancreatitis.胰腺和胆管梗阻会加重大鼠蛙皮素诱导的胰腺炎:一种急性出血性胰腺炎的新实验模型。
J Gastroenterol. 2006 Apr;41(4):352-60. doi: 10.1007/s00535-005-1767-9.
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Natural history of asymptomatic bile duct stones at time of cholecystectomy.胆囊切除术时无症状胆管结石的自然病史。
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Glutathione depletion with L-buthionine-(S,R)-sulfoximine demonstrates deleterious effects in acute pancreatitis of the rat.
Dig Dis Sci. 2002 Aug;47(8):1793-9. doi: 10.1023/a:1016496612906.