Cherniakova V I, Bereza N M, Selezneva S I, Chaplinskiĭ V Ia, Kudriavtseva V E, Mosalova N M, Shevtsova Z I, Tropko L V, Boĭko T I
Mikrobiol Zh (1978). 1993 May-Jun;55(3):63-7.
The results from examination of intestinal microflora and immune status in 75 patients with nonspecific ulcerative colitis with different degree of disease seriousness are presented. The deviations in the composition of normal microflora were primarily expressed in a decrease of the number of bifidobacteria. In 64.9% of patients the disease proceeded against the background of deficit of T-cellular immunity link. The sufficiently expressed bacteriological and immunological efficiency of complex therapy including preparation from spore-forming bacteria as a normalizer of microflora is shown.
本文呈现了对75例不同疾病严重程度的非特异性溃疡性结肠炎患者肠道微生物群和免疫状态的检查结果。正常微生物群组成的偏差主要表现为双歧杆菌数量减少。64.9%的患者疾病在T细胞免疫环节缺陷的背景下进展。研究表明,包括芽孢形成菌制剂作为微生物群正常化剂在内的综合治疗具有充分的细菌学和免疫学疗效。