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[人免疫球蛋白对非特异性溃疡性结肠炎患者大肠菌群的影响]

[Effect of human immunoglobulins on microflora of the large intestine in nonspecific ulcerative colitis].

作者信息

Glad'ko I A, Pinegin B V, Korshunov V M, Khalif I L, Kirkin B V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1986 Mar(3):92-5.

PMID:3518310
Abstract

The use of commercial preparations of human immunoglobulin for the treatment of ulcerous colitis produces a positive effect on the microflora of the large intestine, contributing to the disappearance of Proteus, the lactose-negative forms of enterobacteria and the hemolytic variants of staphylococci, as well as to the increase of the amount of useful indigenous microflora (bifidobacteria and lactobacteria). The quantitative and qualitative improvement of the microflora leads, possibly, to the decrease of the intoxication of the body, improvement in the activity of the intestine and increased vitamin formation, thus giving a pronounced clinical effect and improvement in the endoscopic picture of the mucous membrane of the large intestine, peculiar for this disease.

摘要

使用人免疫球蛋白商业制剂治疗溃疡性结肠炎对大肠微生物群产生积极影响,有助于变形杆菌、乳糖阴性肠杆菌形式和葡萄球菌溶血变体的消失,以及有益的原生微生物群(双歧杆菌和乳杆菌)数量的增加。微生物群的数量和质量改善可能导致身体中毒减轻、肠道活性改善和维生素生成增加,从而产生显著的临床效果,并改善大肠黏膜的内镜图像,这是该疾病所特有的。

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