Robson S C, Gallivan S, Walkinshaw S A, Vaughan J, Rodeck C H
Department of Obstetrics and Gynecology, University College and Middlesex School of Medicine, London, England.
Obstet Gynecol. 1993 Sep;82(3):359-64.
To derive a formula for calculating fetal weight in small for gestational age (SGA) fetuses and to determine prospectively whether the use of such a targeted formula reduces birth weight prediction errors.
Standard ultrasonic measurements were made in 159 SGA fetuses within 7 days of delivery. Three classes of fetal weight formulas (linear, quadratic, and cubic) were fitted to the data using stepwise regression analysis. Birth weight predictions using these three formulas were then compared prospectively with five previously reported formulas in 187 SGA fetuses.
R2 was 0.97 for each of the three derived formulas. The 95% prediction intervals were comparable for the three formulas (eg, cubic model -11.6, 17.8%), and none were statistically superior to previous formulas. Each of the formulas evaluated prospectively had a systematic error and, with the exception of the present study's linear formula, all had percentage errors that varied systematically over the range of actual birth weights.
Clinically useful birth weight predictions can be made in SGA fetuses, although no particular formula estimates birth weight significantly more accurately than any other.
推导一个用于计算小于胎龄(SGA)胎儿体重的公式,并前瞻性地确定使用这种针对性公式是否能减少出生体重预测误差。
在分娩前7天内对159例SGA胎儿进行标准超声测量。使用逐步回归分析将三类胎儿体重公式(线性、二次和三次)拟合到数据中。然后将使用这三种公式的出生体重预测值与之前报道的五种公式对187例SGA胎儿的预测值进行前瞻性比较。
三种推导公式的R2均为0.97。三种公式的95%预测区间相当(例如,三次模型为-11.6,17.8%),且均无统计学上优于先前公式的情况。前瞻性评估的每个公式都存在系统误差,除本研究的线性公式外,所有公式的百分比误差在实际出生体重范围内均有系统变化。
尽管没有特定公式在估计SGA胎儿出生体重方面比其他公式显著更准确,但临床上仍可对SGA胎儿做出有用的出生体重预测。