Combs C A, Jaekle R K, Rosenn B, Pope M, Miodovnik M, Siddiqi T A
Department of Obstetrics and Gynecology, University of Cincinnati School of Medicine, Ohio.
Obstet Gynecol. 1993 Sep;82(3):365-70.
To derive a formula for sonographic estimated fetal weight (EFW) based on a two-compartment model of fetal volume and to test it against two widely used formulas, especially at the extremes of fetal weight for which existing formulas are generally inaccurate.
We analyzed 865 consecutive sonograms that met the following inclusion criteria: singleton pregnancy, normal anatomy, delivery within 3 days of sonography, and measurements of biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), and femur length (FL). The weight of the fetal head was modeled to be proportional to HC3, and the weight of the trunk proportional to AC2 x FL. The proportionality constants were found by multiple linear regression on 380 sonograms performed in 1990 (the "derivation set"). The new formula was tested for accuracy of prediction of actual birth weight against the formulas of Hadlock et al and Shepard et al using 485 sonograms from 1991-1992 (the "validation set").
In the derivation set, the formula EFW = (0.23718 x AC2 x FL) + (0.03312 x HC3) was fit; the correlation with actual birth weight had an r value of 0.996. In the validation set, the new formula produced smaller systematic errors and smaller absolute errors than either the Hadlock or Shepard formula both overall and in fetal weight strata from less than 1000 g to over 4000 g.
The new formula makes geometric sense and provides accurate estimates of fetal weight across a broad range of weights.
基于胎儿体积的两室模型推导超声估计胎儿体重(EFW)公式,并与两个广泛使用的公式进行比较,特别是在现有公式通常不准确的胎儿体重极端值情况下。
我们分析了865例连续超声检查图像,这些图像符合以下纳入标准:单胎妊娠、解剖结构正常、超声检查后3天内分娩,以及双顶径(BPD)、头围(HC)、腹围(AC)和股骨长度(FL)的测量值。胎儿头部重量建模为与HC³成正比,躯干重量与AC²×FL成正比。通过对1990年进行的380例超声检查图像(“推导集”)进行多元线性回归来确定比例常数。使用1991 - 1992年的485例超声检查图像(“验证集”),将新公式与Hadlock等人和Shepard等人的公式进行比较,以测试其对实际出生体重预测的准确性。
在推导集中,拟合出公式EFW =(0.23718×AC²×FL)+(0.03312×HC³);与实际出生体重的相关性r值为0.996。在验证集中,新公式在总体上以及在小于1000g至超过4000g的胎儿体重分层中,产生的系统误差和绝对误差均小于Hadlock公式或Shepard公式。
新公式具有几何意义,并且在广泛的体重范围内能准确估计胎儿体重。