Gibbs R S
Department of Obstetrics and Gynecology, University of Colorado Health Sciences Center.
Am J Obstet Gynecol. 1993 Aug;169(2 Pt 2):460-2. doi: 10.1016/0002-9378(93)90341-f.
An improved understanding of bacterial vaginosis and of clinical intraamniotic infection and histologic chorioamnionitis has produced data showing strong associations among these conditions. It has recently been shown that the microorganisms in both bacterial vaginosis and clinical intraamniotic infection are similar, of which anaerobes, Gardnerella vaginalis, and Mycoplasma hominis are the predominant organisms in both. Furthermore, in the amniotic fluid of women with intraamniotic infection, strong associations among anaerobes, G. vaginalis, and M. hominis have recently been observed. In two epidemiologic studies (one in a high-risk group of women in labor and another in a lower risk group of antepartum women), the presence of bacterial vaginosis has been associated with the development of intraamniotic infection. Additional recent studies have provided new evidence that histologic inflammation of the placental membranes is associated with both clinical intraamniotic infection and positive cultures of the placenta. Multiple logistic regression analysis has shown a relationship between isolation of organisms from the chorioamnion and bacterial vaginosis.
对细菌性阴道病、临床羊膜腔内感染和组织学绒毛膜羊膜炎的进一步了解产生了数据，表明这些病症之间存在密切关联。最近的研究表明，细菌性阴道病和临床羊膜腔内感染中的微生物相似，其中厌氧菌、阴道加德纳菌和人型支原体是两者中的主要微生物。此外，在羊膜腔内感染女性的羊水样本中，最近观察到厌氧菌、阴道加德纳菌和人型支原体之间存在密切关联。在两项流行病学研究中（一项针对高危分娩女性群体，另一项针对低风险的产前女性群体），细菌性阴道病的存在与羊膜腔内感染的发生有关。最近的其他研究提供了新的证据，表明胎盘膜的组织学炎症与临床羊膜腔内感染和胎盘阳性培养物均有关。多元逻辑回归分析显示，从绒毛膜羊膜中分离出微生物与细菌性阴道病之间存在关联。
