Hakola H P, Puranen M, Repo L, Tiihonen J
Department of Forensic Psychiatry, University of Kuopio, Kuopio University Hospital, Finland.
Dementia. 1993 Mar-Apr;4(2):109-12. doi: 10.1159/000107305.
Long-term effects of bilateral prefrontal lesions were studied in 14 lobotomized schizophrenic patients who were operated in the fifties. CT scans revealed cystic bilateral frontal lesions in almost every patient and cortical atrophy was seen in 5 patients. The prefrontal syndrome was severe in 1 patient, marked in 1 patient, mild in 9 patients and absent in 3 patients. Primitive reflexes could be elicited in 2 patients, 3 patients suffered from epileptic seizures, and 8 from minor motor defects. Four patients committed a homicide in the period after the operation, which indicates that the frequency of committing homicidal acts had doubled when compared with the situation before the operation. The incidence of homicides after lobotomy is extremely high considering that all patients except 1 were kept under continuous observation in hospitals.
对14名在五十年代接受手术的额叶切除术后的精神分裂症患者进行了双侧前额叶病变的长期影响研究。CT扫描显示几乎每位患者都有双侧额叶囊性病变，5名患者出现皮质萎缩。1名患者前额叶综合征严重，1名患者明显，9名患者轻度，3名患者无此症状。2名患者可引出原始反射，3名患者患有癫痫发作，8名患者有轻微运动缺陷。4名患者在术后期间实施了杀人行为，这表明与手术前相比，实施杀人行为的频率增加了一倍。考虑到除1名患者外所有患者都在医院持续接受观察，额叶切除术后杀人行为的发生率极高。
