Nilsson H, Ekberg O, Sjöberg S, Olsson R
Department of Neurology, University of Lund, General Hospital, Malmö, Sweden.
Dysphagia. 1993;8(3):239-43. doi: 10.1007/BF01354545.
Pharyngeal constrictor paresis (PHCP) is sometimes found in videoradiography of the swallowing act in patients complaining of dysphagia. Ten patients with PHCP and 10 dysphagic, age- and sex-matched controls with normal videoradiography were neurologically evaluated and examined with magnetic resonance imaging (MRI) of the brain and brainstem in order to learn the pathogenetic process behind PHCP. The study revealed 8 PHCP patients and 1 dysphagic control with abnormal clinical neurological findings such as myopathy, cerebrovascular disease, or extrapyramidal disease. The neurological examination revealed considerable information of prognostic and therapeutic value in PHCP patients. The MRI was abnormal in 7 PHCP patients and 4 dysphagic controls. However, the findings in MRI were nonspecific but the examination was found to be valuable in selected cases. It is concluded that PHCP is an indicator of neurological disease and accordingly, such patients should be examined by a neurologist to establish the cause of the disease.
咽缩肌麻痹(PHCP)有时在主诉吞咽困难患者的吞咽动作视频造影检查中被发现。对10例PHCP患者和10例吞咽困难且年龄及性别匹配、视频造影正常的对照者进行了神经学评估,并进行了脑部和脑干的磁共振成像(MRI)检查,以了解PHCP背后的发病机制。研究发现8例PHCP患者和1例吞咽困难对照者有异常的临床神经学表现,如肌病、脑血管疾病或锥体外系疾病。神经学检查揭示了对PHCP患者有预后和治疗价值的大量信息。7例PHCP患者和4例吞咽困难对照者的MRI检查结果异常。然而,MRI检查结果是非特异性的,但在某些特定病例中该检查被发现是有价值的。结论是PHCP是神经疾病的一个指标,因此,此类患者应由神经科医生进行检查以确定病因。