Ohneda O, Yanai N, Obinata M
Department of Cell Biology, Tohoku University, Sendai, Japan.
Exp Cell Res. 1993 Sep;208(1):327-31. doi: 10.1006/excr.1993.1253.
Fetal liver stromal cells established from 13-day-old embryos support erythropoiesis in vitro in combination with erythropoietin (Epo). Epo stimulated growth of these stromal cells in a dose-dependent manner and mRNA for Epo receptor was detected. These results suggest the possible involvement of Epo in the generation of the fetal erythropoietic microenvironment during development.