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Erythropoietin as a mitogen for fetal liver stromal cells which support erythropoiesis.

作者信息

Ohneda O, Yanai N, Obinata M

机构信息

Department of Cell Biology, Tohoku University, Sendai, Japan.

出版信息

Exp Cell Res. 1993 Sep;208(1):327-31. doi: 10.1006/excr.1993.1253.

Abstract

Fetal liver stromal cells established from 13-day-old embryos support erythropoiesis in vitro in combination with erythropoietin (Epo). Epo stimulated growth of these stromal cells in a dose-dependent manner and mRNA for Epo receptor was detected. These results suggest the possible involvement of Epo in the generation of the fetal erythropoietic microenvironment during development.

摘要

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