Perroni D, Grecchi G L, La Ciura P, Landoni F
Ospedale Santa Croce, USSL No. 58, Cuneo, Italy.
Eur J Surg Oncol. 1993 Aug;19(4):378-81.
A previously healthy gravida developed chest pain and progressive dyspnea several months after delivery. A right ventricular mass rising from the septum and floating through the pulmonary valve was detected, with multiple lung nodules. With the suspicion of a primary sarcoma of the heart, she was referred for cardiac surgery. Microscopic observation of the cardiac neoplasm revealed malignant trophoblast. There was no evidence of disease in the uterus and adnexa. Combination chemotherapy with EMA-CO schedule was instituted because of the high-risk score. A complete recovery was achieved after 20 weeks of treatment and the patient is free of disease 4 years after the end of chemotherapy and is now pregnant again.
一名既往健康的孕妇在产后数月出现胸痛和进行性呼吸困难。检测发现一个从室间隔长出并穿过肺动脉瓣的右心室肿块,同时伴有多个肺结节。因怀疑原发性心脏肉瘤,她被转诊至心脏外科。对心脏肿瘤的显微镜观察显示为恶性滋养层细胞。子宫和附件未发现疾病迹象。由于高危评分,采用EMA-CO方案进行联合化疗。治疗20周后完全康复,化疗结束4年后患者无疾病复发,现已再次怀孕。