Guslandi M, Sorghi M, Foppa L, Tittobello A
Gastroenterology Unit, S. Raffaele Hospital, University of Milan, Italy.
Digestion. 1993;54(3):160-2. doi: 10.1159/000201031.
In order to investigate some pathophysiological aspects of the two diseases, 15 patients with congestive gastropathy and 15 with chronic gastritis have been studied and compared with 15 healthy controls. Gastric blood flow as determined during endoscopy by means of laser Doppler flowmetry was found to be significantly increased (p < 0.001) in congestive gastropathy, whereas a significant reduction (p < 0.001) was noted in chronic gastritis. On the other hand, Helicobacter pylori was detected in 80% of cases in chronic gastritis, while the prevalence of the microorganism in congestive gastritis was similar to that in healthy controls. It is concluded that chronic gastritis and congestive gastropathy are related to different pathogenetic factors and require different therapeutic approaches.
为了研究这两种疾病的一些病理生理方面,对15例充血性胃病患者和15例慢性胃炎患者进行了研究,并与15名健康对照者进行了比较。在内镜检查期间通过激光多普勒血流仪测定的胃血流量在充血性胃病中显著增加(p < 0.001),而在慢性胃炎中则显著降低(p < 0.001)。另一方面,在80%的慢性胃炎病例中检测到幽门螺杆菌,而充血性胃炎中该微生物的患病率与健康对照者相似。得出的结论是,慢性胃炎和充血性胃病与不同的致病因素有关,需要不同的治疗方法。