Dassy B, Hogan T, Foster T J, Fournier J M
Département d'Ecologie, Institut Pasteur, Paris, France.
J Gen Microbiol. 1993 Jun;139 Pt 6:1301-6. doi: 10.1099/00221287-139-6-1301.
The effect of an agr mutation on expression of type 5 capsular polysaccharide (CP) by Staphylococcus aureus Newman was investigated in different complex and synthetic media. CP expression by the agr mutant was strongly reduced in certain media but slightly in others, indicating that CP synthesis is positively controlled by agr. CP expression occurred in the post-exponential growth phase in both wild-type and mutant strains, suggesting that other regulatory systems could act in conjunction with agr.
研究了agr突变对金黄色葡萄球菌Newman菌株5型荚膜多糖（CP）表达的影响，实验在不同的复合培养基和合成培养基中进行。agr突变体的CP表达在某些培养基中显著降低，但在其他培养基中略有降低，这表明CP合成受到agr的正向调控。野生型和突变株的CP表达均发生在指数生长后期，这表明其他调节系统可能与agr共同发挥作用。
