Davies J, Everall I P, Lantos P L
Department of Neuropathology, Institute of Psychiatry, London, U.K.
J Neural Transm Suppl. 1993;39:77-85.
This paper addresses the issues in establishing a contemporary AIDS Brain Bank with a Database. It draws comparisons from the past when a similar approach was made towards the understanding of mental illness and its treatment. The aim of the Brain Bank is to provide a comprehensive range of neuropathologically characterised tissues from the nervous system to researchers and scientists as a resource for research. The aim of the Database is to provide the up-to-date clinical and pathological information relating to the material supplied by the Brain Bank. The paper describes the mechanics of establishing the Database, the importance of efficiency as well as discussing the sensitive issues that need to be addressed when designing and AIDS Database and Brain Bank.
本文探讨了建立一个带有数据库的当代艾滋病脑库所涉及的问题。它借鉴了过去在理解精神疾病及其治疗方面采取类似方法的情况。脑库的目的是为研究人员和科学家提供一系列全面的、经过神经病理学特征描述的神经系统组织,作为研究资源。数据库的目的是提供与脑库所提供材料相关的最新临床和病理信息。本文描述了建立数据库的机制、效率的重要性,并讨论了设计艾滋病数据库和脑库时需要解决的敏感问题。