Tammiala-Salonen T, Söderling E
Institute of Dentistry, University of Turku, Finland.
Scand J Dent Res. 1993 Aug;101(4):215-8. doi: 10.1111/j.1600-0722.1993.tb01107.x.
Resting and stimulated whole saliva and parotid saliva of men and pre- and post-menopausal women with burning mouth syndrome (BMS) and their matched controls were studied. Women with BMS had slightly, but not significantly, higher flow rates than their controls. The total protein concentration in stimulated saliva of women with BMS was significantly lower than that of controls. This difference was not associated with the flow rate. The proportional amount of sialic acid, used as an indicator of mucin concentration, was higher in subjects with BMS than in their controls. SDS-PAGE showed no consistent differences in the protein profiles of saliva, nor were any differences observed in the adhesion or agglutination assays between subjects with BMS and their matched controls. Thus, the present results indicate that BMS is not associated with a decrease in the protecting and lubricating properties of saliva.
对患有灼口综合征（BMS）的男性以及绝经前后的女性及其匹配的对照组的静息和刺激状态下的全唾液和腮腺唾液进行了研究。患有BMS的女性的唾液流速略高于其对照组，但差异不显著。患有BMS的女性刺激唾液中的总蛋白浓度显著低于对照组。这种差异与流速无关。用作粘蛋白浓度指标的唾液酸比例在患有BMS的受试者中高于其对照组。SDS-PAGE显示唾液的蛋白质谱没有一致的差异，在患有BMS的受试者与其匹配的对照组之间的粘附或凝集试验中也未观察到任何差异。因此，目前的结果表明，BMS与唾液的保护和润滑特性降低无关。
