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麻疹感染导致的颞骨组织病理学变化。

Histopathologic changes in the temporal bone resulting from measles infection.

作者信息

Bordley J E, Kapur Y P

出版信息

Arch Otolaryngol. 1977 Mar;103(3):162-8. doi: 10.1001/archotol.1977.00780200088010.

DOI:10.1001/archotol.1977.00780200088010
PMID:836245
Abstract

We report the pathologic changes in the temporal bones of four children who died of bronchoppenumonia secondary to acute measles infection. All suffered from severe necrotizing otitis media characterized by round cell infiltration. In one case, multilobulated giant cells (Warthin-Finkelday) were found in the middle ear. These cells appear to be similar to those found elsewhere within the body during acute measles infection. Inner ear changes were seen in two cases. Severe loss of nerve fibers and ganglion cells with atrophy of the striae vascularis was present in one case. Adhesions were seen between the Reissner membrane and the tectorial membrane in one case and the Reissner membrane and the inner spiral limbus in a second case. Such findings are characteristic of those seen in the cochlear duct of persons suffering from prenatal rubella.

摘要

我们报告了4名死于急性麻疹感染继发支气管肺炎的儿童颞骨的病理变化。所有患儿均患有以圆形细胞浸润为特征的严重坏死性中耳炎。在1例患儿的中耳发现了多叶巨细胞(华特林-芬克尔戴细胞)。这些细胞似乎与急性麻疹感染时在体内其他部位发现的细胞相似。2例患儿出现内耳改变。1例患儿存在神经纤维和神经节细胞严重缺失以及血管纹萎缩。1例患儿的Reissner膜与盖膜之间出现粘连,另1例患儿的Reissner膜与内螺旋缘之间出现粘连。这些发现是患先天性风疹者耳蜗管中所见特征。

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