N-（5'-磷酸吡哆醛基）-4-氨基丁酸：大鼠脑4-氨基丁酸转氨酶的一种稳定双底物加合物抑制剂。
N-(5'-Phosphopyridoxyl)-4-aminobutyric acid: a stabel bisubstrate adduct inhibitor of rat brain 4-aminobutyric acid aminotransferase.
作者信息
Tunnicliff G, Ngo T T, Barbeau A
出版信息
Experientia. 1977 Jan 15;33(1):20-2. doi: 10.1007/BF01936728.
PMID:836410
Abstract
N-(5'-Phosphophopyridoxyl)-4-aminobutyric acid, a stable adduct of pyridoxal phosphate and 4-aminobutyrate acid, has been shown to be a potent inhibitor of rat brain 4-aminobutyric acid aminotransferase (GABA-T) with a K1 of 1.4 muM.
摘要
N-(5'-磷酸吡哆醛基)-4-氨基丁酸是磷酸吡哆醛与4-氨基丁酸的稳定加合物，已被证明是大鼠脑4-氨基丁酸转氨酶（GABA-T）的强效抑制剂，其抑制常数（K1）为1.4微摩尔。
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