Hellgren L, Larsson K
Experientia. 1977 Jan 15;33(1):97-8. doi: 10.1007/BF01936775.
Small bipsies of the skin were taken from patients with papulo-cutaneous mastocytosis. The mast cell tumours were then degranulated with compound 48/80 (250 mug/ml in saline), and with a Sorption microcalorimeter, relatively strong exothermic reactions were measured, whereas normal skin showed only 1/10th the intensity. Disodium chromoglicate (1%) had no inhibitory effect on this thermal reaction.
从丘疹性皮肤肥大细胞增多症患者身上取小块皮肤组织。然后用48/80化合物(在生理盐水中为250微克/毫升)使肥大细胞瘤脱颗粒,使用吸附式微量量热计测量到相对较强的放热反应,而正常皮肤的反应强度仅为其十分之一。色甘酸钠二钠(1%)对这种热反应没有抑制作用。