Gasperini M, Scherillo P, Manfredonia M G, Franchini L, Smeraldi E
Department of Neuropsychiatric Sciences, Ospedale San Raffaele, Istituto di Ricovero e Cura a Caratiere Scientifico, University of Milan Medical School, Italy.
Eur Neuropsychopharmacol. 1993 Jun;3(2):103-10. doi: 10.1016/0924-977x(93)90261-j.
In a sample of 213 mood disorder subjects on long-term lithium treatment, we analyzed the recurrence indices of relapses during the prophylactic treatment period. The differences found in the recurrence rates were due to the current age and age of onset, duration of illness and polarity of the probands. The patients with personality disorders showed the worst relapse indices and could represent a group of mood disorder subjects with a bad outcome of lithium treatment.
在213名接受长期锂盐治疗的心境障碍患者样本中,我们分析了预防性治疗期间复发的复发指数。复发率的差异归因于当前年龄、起病年龄、病程以及先证者的极性。患有精神障碍的患者显示出最差的复发指数,可能代表了一组锂盐治疗效果不佳的心境障碍患者。