Haussmann R, Lewitzka U, Severus E, Bauer M
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.
Nervenarzt. 2017 Nov;88(11):1323-1334. doi: 10.1007/s00115-017-0421-0.
Due to their unique therapeutic effects and high efficacy, lithium salts are recommended in guidelines, particularly for the treatment of mood disorders; however, despite the therapeutic efficacy lithium treatment is underutilized in the treatment of these disorders. The therapeutic efficacy of lithium is contrasted by a narrow therapeutic range and a potential risk of intoxication, which is why close drug monitoring is necessary during lithium treatment. Furthermore, lithium therapy requires well-founded knowledge about patient selection with respect to approved areas of administration and indications. This review article summarizes clinically relevant knowledge of lithium treatment to improve treatment of patients with mood disorders and to increase patient safety when using lithium.
由于锂盐具有独特的治疗效果和高效性,在指南中被推荐使用,特别是用于治疗情绪障碍;然而,尽管锂盐治疗具有疗效,但在这些疾病的治疗中其使用仍未得到充分利用。锂盐的治疗效果与狭窄的治疗范围和潜在的中毒风险形成对比,这就是为什么在锂盐治疗期间需要密切进行药物监测的原因。此外,锂盐治疗需要对患者选择、批准的给药领域和适应症有充分的了解。这篇综述文章总结了锂盐治疗的临床相关知识,以改善情绪障碍患者的治疗,并在使用锂盐时提高患者安全性。