Bartsch G, Rohr H P
Invest Urol. 1977 Jan;14(4):301-6.
Stereology is a method used to obtain quantitative information of structural changes at the light and electron microscopic level. The basic principles of stereology are outlined below. This paper shows how stereologic techniques can be used to obtain structural data from histologic and electron micrographs of intact tissue and cells. A morphometric model, which provides information on the structure of the prostatic gland has been developed for the rat prostate. The model consists of morphologically defined space and membrane compartments of the prostatic gland and the glandular cells. The alterations, induced in the glandular cells of the ventral lobe of rat prostate by the administration of a synthetic progestin (ethinyl-norgestrienone), were studied by electron microscopy. The results presented are relative to a cubic centimeter of prostatic tissue, a cubic centimeter of acinar parenchyma, and glandular cell cytoplasm. An attempt to relate stereologic and biochemical data is shown.
体视学是一种用于在光学和电子显微镜水平上获取结构变化定量信息的方法。下面概述体视学的基本原理。本文展示了如何使用体视学技术从完整组织和细胞的组织学和电子显微照片中获取结构数据。已经为大鼠前列腺开发了一种形态计量模型，该模型提供有关前列腺结构的信息。该模型由前列腺和腺细胞的形态学定义的空间和膜隔室组成。通过电子显微镜研究了合成孕激素（炔诺孕酮）给药对大鼠前列腺腹叶腺细胞的影响。给出的结果是相对于一立方厘米的前列腺组织、一立方厘米的腺泡实质和腺细胞胞质而言的。展示了将体视学数据与生化数据相关联的尝试。
