Toyama M, Ueki K, Honda H
No Shinkei Geka. 1978 Nov;6(11):1109-12.
A case of spontaneous pontine hematoma in young boy, with remitting and relapsing clinical course of up to 11 years, suspected of having pontine glioma or multiple sclerosis is reported. Differential diagnosis of these are mentioned with reference to our cases of pontine glioma. This patient was a man aged 16. At 5 years of age he had his first episode of double vision. 20 days after first episode, gait disturbance, left facial palsy and consciousness disturbance developed. Neurological and neuroradiological examination revealed a pontine glioma and radiotherapy was administered. All signs and symptoms resolved except for bilateral abducens palsy. Four months later, he again complained of gait disturbance and facial palsy. Examination revealed bilateral conjugate ocular palsy, left facial palsy and cerebellar ataxia. These symptoms again resolved spontaneously, except for bilateral abducens palsy. At age 16 years, having been asymptomatic for 10 years, he suddenly noticed loss of taste. At that time sensory disturbance of the left side of himself, right hearing disturbance, dysarthria and retardation urinae. Neurological examination revealed bilateral optic atropy, bilateral abducens palsy, left facial palsy, right hyperacuisis, dysarthria, left hemiparesis, hypesthesia of the left side of the body and left cerebellar ataxia. The vertebral angiography was no evidences of mass lesion and vascular anomalies. The computed tomography demonstrated a pontine hematoma. Conservative therapy was performed and these symptoms cleared off except for bilateral abducens palsy.
报告了一例年轻男孩自发性脑桥血肿病例,其临床病程缓解与复发长达11年,曾怀疑患有脑桥胶质瘤或多发性硬化症。结合我们的脑桥胶质瘤病例提及了这些疾病的鉴别诊断。该患者为16岁男性。5岁时首次出现复视。首次发作20天后,出现步态障碍、左侧面神经麻痹和意识障碍。神经学和神经放射学检查显示为脑桥胶质瘤并进行了放疗。除双侧展神经麻痹外,所有体征和症状均消失。四个月后,他再次抱怨步态障碍和面神经麻痹。检查发现双侧共轭性眼球麻痹、左侧面神经麻痹和小脑共济失调。除双侧展神经麻痹外,这些症状再次自发缓解。16岁时,在无症状10年后,他突然注意到味觉丧失。当时他左侧感觉障碍、右侧听力障碍、构音障碍和排尿迟缓。神经学检查发现双侧视神经萎缩、双侧展神经麻痹、左侧面神经麻痹、右侧听觉过敏、构音障碍、左侧偏瘫、身体左侧感觉减退和左侧小脑共济失调。椎动脉血管造影未发现占位性病变和血管异常。计算机断层扫描显示为脑桥血肿。进行了保守治疗,除双侧展神经麻痹外,这些症状均消失。