[通过脉搏血氧饱和度仪监测苯胺诱导的高铁血红蛋白血症]

[Aniline-induced methemoglobinemia monitored by pulse oximetry].

作者信息

Kubota M, Soma K, Suzuki M, Hanada N, Takada N, Kusuhara N, Kobayashi H, Yanase N, Abe T, Tomita T

机构信息

Department of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1993 Jul;31(7):886-9.

PMID:8366629

Abstract

A case of aniline-induced methemoglobinemia is reported. When the pulse oximeter reading (SpO2) was 80%, the oxygen saturation measured by a co-oximeter (SaO2) was 61.2%, the oxygen saturation calculated from PaO2 values was 98.9% and methemoglobin level was 38.8%. After methylene blue injection, methemoglobin level decreased gradually. With a decrease of methemoglobin level, SpO2 approached SaO2. If disparity between SpO2 and the oxygen saturation calculated from PaO2 values is noted, the presence of methemoglobinemia must be suspected. In clinical situations, the pulse oximeter permits the continuous noninvasive monitoring of oxygen saturation. It is necessary, however, to consider the potential errors in pulse oximetry.

摘要

报告了一例苯胺引起的高铁血红蛋白血症病例。当脉搏血氧饱和度仪读数（SpO2）为80%时，经血气分析仪测定的血氧饱和度（SaO2）为61.2%，根据动脉血氧分压（PaO2）值计算出的血氧饱和度为98.9%，高铁血红蛋白水平为38.8%。注射亚甲蓝后，高铁血红蛋白水平逐渐下降。随着高铁血红蛋白水平的降低，SpO2接近SaO2。如果注意到SpO2与根据PaO2值计算出的血氧饱和度之间存在差异，则必须怀疑存在高铁血红蛋白血症。在临床情况下，脉搏血氧饱和度仪可对血氧饱和度进行连续无创监测。然而，有必要考虑脉搏血氧测定法中可能存在的误差。