Higginson J
Am J Pathol. 1977 Feb;86(2):460-84.
The present paper summarizes the role of the morbid anatomist and clinical pathologist in environmental carcinogenesis. It points out that in the past he has contributed considerably to the identification of rare tumors and their etiology. He has an important role to play in the future in providing more accurate data on which epidemiology studies can be developed. The view is also expressed that it is highly important that modern pathologists have an understanding of toxicologic and pharmacologic techniques and their potential application to biologic material in order that they may be in a position to correlate and develop multidisciplinary approaches to the identification of environmental hazards. Some of these approaches are illustrated and their potential developments outlined.
本文总结了病理解剖学家和临床病理学家在环境致癌作用中的作用。指出过去他们在识别罕见肿瘤及其病因方面做出了相当大的贡献。未来,他们在提供更准确的数据以便开展流行病学研究方面将发挥重要作用。文中还表达了这样一种观点,即现代病理学家了解毒理学和药理学技术及其在生物材料中的潜在应用非常重要,以便他们能够关联并发展多学科方法来识别环境危害。文中举例说明了其中一些方法,并概述了它们的潜在发展。