Thomson W M, Brown R H, Williams S M
Public Health Unit, Manawatu-Wanganui Area Health Board, Palmerston North.
N Z Med J. 1993 Jun 9;106(957):219-21.
(1) To estimate the prevalence of use of different medication categories; (2) to estimate the prevalence of xerostomia (dry mouth); and (3) to estimate the effects of xerostomic medication upon perceived dry mouth among institutionalised elderly people.
A two-stage stratified random sample of three hundred and fifty-nine people aged 65 to 102 living in rest homes and geriatric hospitals in the Manawatu and Horowhenua districts.
Subjects were interviewed and dentally examined at their place of residence. Medication was noted from institutional records, and subjects' experiences of xerostomia were explored using the question "how often does your mouth feel dry?"
The sample was found to be highly medicated, with a mean 3.6 different drugs per individual, and only 10% not taking any medication. Psychotherapeutics (42.3%), analgesics (32.9%), diuretics (31.2%) and laxatives (23.4%) were the most common drug categories. Of the 284 subjects who were able to answer, only those who were taking anticholinergic medication reported a higher prevalence of xerostomia.
Institution-dwelling elderly people are a highly-medicated group. There is an increased risk of unwanted oral side-effects with certain drugs, and it is recommended that this is borne in mind when prescribing for elderly patients.
(1)评估不同药物类别的使用 prevalence;(2)评估口干症(口干)的 prevalence;(3)评估在机构养老的老年人中,引起口干的药物对自觉口干的影响。
对马纳瓦图和霍罗韦纳地区养老院和老年医院中359名年龄在65至102岁之间的老人进行两阶段分层随机抽样。
在受试者居住地点对其进行访谈和牙科检查。从机构记录中记录用药情况,并通过询问“您的口腔感觉干燥的频率如何?”来探究受试者的口干经历。
发现样本的用药率很高,每人平均使用3.6种不同药物,只有10%的人未服用任何药物。精神治疗药物(42.3%)、镇痛药(32.9%)、利尿剂(31.2%)和泻药(23.4%)是最常见的药物类别。在能够回答的284名受试者中,只有服用抗胆碱能药物的受试者报告口干症的 prevalence 较高。
居住在机构中的老年人是用药率很高的群体。某些药物产生不良口腔副作用的风险增加,建议在为老年患者开处方时牢记这一点。