用豚鼠腹腔渗出细胞转移实验性变应性脑脊髓炎
Transfer of experimental allergic encephalomyelitis with guinea pig peritoneal exudate cells.
作者信息
Driscoll B F, Kies M W, Alvord E C
出版信息
Science. 1979 Feb 9;203(4380):547-8. doi: 10.1126/science.83676.
PMID:83676
Abstract
Incubation with specific antigen, myelin basic protein, greatly enhances the ability of guinea pig peritoneal exudate cells to transfer experimental allergic encephalomyelitis. Reproducibly successful transfers are obtained with 10(7) cells. With this relatively small number of cells, in vitro studies to determine the immunologic mechanisms involved in the disease process are now possible.
摘要
与特异性抗原髓磷脂碱性蛋白一起孵育，可极大地增强豚鼠腹腔渗出细胞转移实验性变应性脑脊髓炎的能力。用10⁷个细胞可重复性地成功实现转移。利用这相对少量的细胞，现在就有可能进行体外研究以确定疾病过程中涉及的免疫机制。
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